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Grey Turner’s sign refers to bruising of the flanks. The bruising appears as a blue discoloration, and is a sign of retroperitoneal hemorrhage, or bleeding behind the peritoneum, which is a lining of the abdominal cavity. Grey Turner’s sign takes 24–48 hours to develop, and can predict a severe attack of acute pancreatitis.

Causes include

  • Acute pancreatitis
  • Pancreatic hemorrhage
  • Retroperitoneal hemorrhage
  • Blunt abdominal trauma
  • Ruptured / hemorrhagic ectopic pregnancy.
  • Spontaneous bleeding secondary to coagulopathy (congenital or acquired)
  • Aortic rupture, from ruptured abdominal aortic aneurysm or other causes.
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