Koeppe nodules, seen at the inner margin of the iris in patients with granulomatous anterior uveitis. The condition may develop in diseases like sarcoidosis, tuberculosis, syphilis, and Vogt Koyanagi Harada Syndrome. Lyme disease, leprosy, and brucellosis, may also be considered in endemic areas. The nodules are composed of epithelioid cells and giant cells surrounded by lymphocytes.
Option A: Lisch nodules: These are gold-tan to brown coloured, dome-shaped gelatinous masses developing on the surface of the iris. They are seen in patients with NF-I
Option B: Busacca nodules: These are usually larger nodules located on the mid periphery of the iris. These occur due to granulomatous inflammatory conditions similar to that of Koeppe nodules.
Option D: Dalen-Fuchs nodules: These are clusters of epithelioid cells containing pigment lying between the RPE (Retinal Pigment Epithelium) and Bruch’s membrane (Innermost layer of the choroid), seen in Sympathetic Ophthalmia.